RNA Details
Disease Name
scleroderma systemic
Tissue
skin
RNA Symbol
mir-21a
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
RT-PCR; transfection experiments; etc.
Target
MIR-21; MIR-29S
Pathway
NA
PubMed ID
Title
MicroRNA-21 and microRNA-29a modulate the expression of collagen in dermal fibroblasts of patients with systemic sclerosis
Year
2019
Function
Focusing on mir-21 and mir-29s as therapeutic targets would be effective in patients with ssc or other fibrotic diseases which show aberrant expression of collagen expression.